Current UV Index
UV index: 0.0
Alice Springs
UV index: 0.0
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Gold Coast
UV index: 0.0
UV index: 0.0
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Click the indexes to view the minimum recommended protection

When the UV index is low, sun protection is generally not needed unless outside for extended periods

UV observations courtesy of ARPANSA

Targeted Therapy

What is Targeted Therapy?

Targeted cancer therapies work by interfering with specific molecules ("molecular targets") that are involved in the growth, progression and spread of the cancer.   Most targeted therapies are 'cytostatic' meaning they block cancer cell proliferation, rather than cytotoxic (eg. chemotherapy), which kills tumour cells.

B-Raf/MEK Therapies
Approximately 40% of melanoma patients contain an altered form of a growth signalling protein known as the B-Raf protein.   If a patient's tumor is shown to contain this protein, the patient is deemed B-Raf positive and may receive a treatment that targets this specific altered protein.   Unfortunately cancer cells tend to become resistant to these therapies. For this reason, they are often used in combination ie. more than one drug at a time.

Targeted Therapy Side Effects


Targeted cancer therapies can have substantial side effects.  They are most commonly

  • Skin problems (acneiform rash, dry skin, nail changes, hair depigmentation)
  • Diarrhoea
  • Liver problems such as hepatits and elevated liver enzymes
  • Problems with blood clotting and wound healing
  • High blood pressure
  • Gastrointestinal perforation (a rare side effect of some targeted therapies)